Anybody that thought the genome was going to directly provide drugs was a fool. Biological

networks are not simple, and making drugs to affect them won't be simple.
Leroy Hood

I'm more in that Rafa Nadal high-energy high-octane mold out there. I wear that emotion on the court. That's how I play my best tennis. People either like that or not. And I can't change that: that's who I am on a tennis court.
Lleyton Hewitt

In many ways, 'William Shakespeare's Star Wars' is modeled on Shakespeare's Henry V, which relied on a chorus to explain in words the battles of Harfleur and Agincourt that could never be captured on the Elizabethan stage.
Ian Doescher

To be honest, accents are one of those things for me, personally, that usually come quite naturally by just listening to the people.
Laura Donnelly

How many persons condemned to the horrors of solitary confinement have gone mad - simply because the thinking faculties have lain dormant!
Jules Verne

I don't go to the mall a lot 'cause girls scream and run at me, and I get shy.
Paul Butcher

I can be a show-off at home. But publicly, I have always been a private person. It's not totally my bag to court the press.
Jade Jagger

My father's really fluent in French, but I can't speak at all. I actually took it twice in school already and failed both times!
Jean-Luc Bilodeau

My criteria when looking for a role is that I will do anything that stands the chance of succeeding on the level it is intended to. After that, if it's a part I can do something personal with.
John Hurt

I meditate. I've been a meditator since, I think I was doing it unofficially before all my life and then began to formalize it somewhere around 14.
Lorraine Toussaint

Relative to most of the energy and material flows on Earth, the machinations of humankind are puny. The planet's powers are much, much bigger than our own. But in a few sensitive places, we're making an impact on a planetary scale, and that impact is not a good one.
Donella Meadows

Gemeoss

For those who are able to work, work has to be seen as the best

route out of poverty. For work is not just about more money - it is transformative. It's about taking responsibility for yourself and your family. Iain Duncan Smith I like making songs up. Whether or not they're great songs or good songs, whatever. It's something I've always done, and I definitely feel like I've gotten better at it. Jeff Tweedy It's interesting that so many books now are published as the first in a series. It never occurred to me. Although 'The Giver' does have an ambiguous ending. I've heard about that from readers over the years. Lois Lowry I no longer buy papers or tabloids or magazines or read blogs. I used to. But it was just filling up my day with hatred. Adele When I get dolled up to go out, men turn their heads and I'm used to it. But I think all women are sexy and should embrace that side of themselves. Malin Akerman With fitness, I do Bikrams hot yoga. The gym that I have in my building is amazing. I love...

The public is upset. If they haven't lost their job, they know somebody that has.

If they haven't lost their house, they know somebody that has. What do you do? When something's wrong, it's government's job to fix it, it must be government that's responsible for causing it. Michael Bloomberg People who are pierced should not be snickered at, should not become the object of ridicule, should not be singled out for special and uneven and unequal treatment. They should be respected just like everybody else. Gloria Allred Usually when I'm making a movie, what I have in mind first, for the visuals, is how we can stage the scenes to bring them more to life in the most interesting way, and then how we can make a world for the story that the audience hasn't quite been in before. Wes Anderson Yoga is the settling of the mind into silence. When the mind has settled, we are established in our essential nature, which is unbounded Consciousness. Our essential nature is usually overshadowed by the activity of the mind. Patanjali You can rest...

One of the things I try to do with my writing is try to evoke

the spirit of the place. I think these things imprint on the landscape and the culture. Sarah Hall I'm not the kind of filmmaker who's going to go from one thing to the next. I often wish I was that filmmaker, but I'm just not. Jonathan Glazer Once I'm on stage, there's just no time for a sip of water - I've always got my hands in puppets! My voice is raw by the time I finish. Nina Conti When the Mets were on their run in the 1980s, Gary Carter was often seen hugging somebody. It was easy to joke about that. The best hug of all was with Jesse Orosco at the end of the 1986 World Series. George Vecsey I do love the evolution of people in general. I think it's a beautiful thing when someone progresses and evolves in life. Khloe Kardashian There are over 50 brilliant scientists working at my lab, and being sensitive to their needs is among the top skill sets that scientists like me have to learn. Peter Agre I am well aware that there are prison...

One of the most painful things in the Western States and Territories is the extinction

of childhood. I have never seen any children - only debased imitations of men and women, cankered by greed and selfishness, and asserting and gaining complete independence of their parents at ten years old. Isabella Bird What I would say to young entrepreneurs is there's so many moments in your life where you have these dreams, and people are trying to protect you, and they say, perhaps, friends, family, parents sometimes, they don't agree with it, they think, 'This is just too high of a hurdle.' And I don't agree with that. Howard Schultz Being shoved into the top-40 scene was an unusual experience. It was great I'd become accessible to a huge audience but not terribly fulfilling. David Bowie There is no shame in my saying that we all want to be loved by someone. As I look back over my life in romance, I don't feel I've ever had that. Sean Penn I like Jay-Z, 50 Cent and Common. But I like the underground stuff like Young Jeezy, Black Rob and...

Many believe - and I believe - that I have been designated for this work

by God. In spite of my old age, I do not want to give it up; I work out of love for God and I put all my hope in Him. Michelangelo The greatest problem all around the world today, whether in America, Japan, China Russia, India or anywhere else in the world, is that people are not in peace. People want peace. Prem Rawat Through selfless work, love of God grows in the heart. Then through his grace one realize him in course of time. God can be seen. One can talk to him as I am talking to you. Ramakrishna A wartime Minister of Information is compelled, in the national interest, to such continuous acts of duplicity that even his natural hair must grow to resemble a wig. Claud Cockburn I think she said I should seek help. Something like that, but it was in much cruder terms. And that I had a fascination with things coming out of people's mouths. Sam Raimi You know, if you're lucky enough to have two smash hit shows, the traffic of the world goes through your dressing r...

The strategy of my coach and me was that we looked at pictures

of all the best pole vaulters from around the world, and we took the best parts from them, and we created a person that had never existed. We then started to work toward being such a person. Sergei Bubka I have a completely addictive personality. Diet Coke is my last - God, I know people counting days off Diet Coke; I'm such a Diet Cokehead. Now I won't let myself buy it. Mary Karr Take a random selection of photographs of America in 2012 and 2002 and 1992 and, except for the skinny jeans and the porkpie hats, you'll be hard-pressed to tell the years in which the pictures were taken. Graydon Carter Trust me, I did not set out to establish three pen names and, for the record, I do not recommend it as a career strategy. The idea back at the start was that I would stick with the name that proved most successful. Jayne Ann Krentz I remember when I thought of singing as the bit that went between the guitar playing - something I couldn't wait to get out of the way...

What formed me as a musician, a songwriter, the sound and personality of

my band, a whole lot of that happened well before 1991. Chris Cornell For me, integrity is the consistency of words and actions. Part of the way that you do that is to ask people questions on some of the most difficult issues that you confront. 'Take me through where you felt you had to compromise your values.' Kenneth Chenault He who improves an opportunity sows a seed which will yield fruit in opportunity for himself and others. Orison Swett Marden I have been doing this since I was 10 years old. It wasn't like I was an overnight hit. I think when that happens to some actors - they just don't know what to do with themselves. You don't know how to cope with friends and all of a sudden not being able to go out. It's such a shock to your system. Eliza Dushku One of the reasons that I take such joy in being a trustee of the New York Public Library is the love of reading that I found as a child in the Saturday morning library events for preschoolers and...

You know, I am mainstream America, and it really doesn't matter what party you're in.

When you call your children and you say 'How are you?' - and what you are really asking is, 'Do you still have your job? And are you able to make the mortgage payment?', That resonates across the state, not across party lines. Sharron Angle We played all of the songs on the first Johnny Winter AND every day before we recorded them, so that when we got in the studio, it was totally easy, as we knew exactly what we wanted to do. Rick Derringer Even as our economy starts to pick up, and new jobs are created, there is a risk that young people in Britain won't get the chances they deserve because businesses will continue to look elsewhere. Iain Duncan Smith I am a United States citizen and I vote. Martha Plimpton I'm still driving a Prius, yeah. Larry David So get accomplished what you want to get accomplished in your life. And in the intervals, do what you can to help other people. Sean Hayes When the good lord calls you home, the government ought ...

Government is a contrivance of human wisdom to provide for human wants. People have the

right to expect that these wants will be provided for by this wisdom. Jimmy Carter Ideology... is indispensable in any society if men are to be formed, transformed and equipped to respond to the demands of their conditions of existence. Louis Althusser Negroes who have been so long inconvenienced and denied opportunities for development are naturally afraid of anything that sounds like discrimination. Carter G. Woodson The credit which the apparent conformity with recognized scientific standards can gain for seemingly simple but false theories may, as the present instance shows, have grave consequences. Friedrich August von Hayek You will find something more in woods than in books. Trees and stones will teach you that which you can never learn from masters. Saint Bernard Our faith is faith in someone else's faith, and in the greatest matters this is most the case. William James The logic of the world is prior to all truth and falsehood. Ludwig Wittgenstein Poli...

The more living patterns there are in a place - a room, a building, or

a town - the more it comes to life as an entirety, the more it glows, the more it has that self-maintaining fire which is the quality without a name. Christopher Alexander As far as loneliness, I feel Los Angeles and its layout, having to drive everywhere - it is a lonely place. It's an isolated city in that respect because you're driving to places alone listening to the radio. Jason Schwartzman I mean, people who say that the Tea Party isn't a grassroots movement, I think, are incorrect. I think in some respects, it is a grassroots movement. Matt Taibbi I see couples fighting about the stupidest things. You just have to rise above everything. Sammy Hagar Making choices that improve things for all of us on the planet is an act of compassion, a simple act we can do any time we go shopping. Daniel Goleman I can't stand the kind of paralysis that some people fall into because they're not happy with the choices they've made. Hillary Clinton As a ki...